These chews are very strong, so we recommend starting with 1/4 of a chew and allowing one hour for onset of effects.Our Sativa Chew cannabinoid concentration results in a lighter, more energetic feeling. These chews are excellent for daytime pain relief. Our Indica Chew is great for relaxation, stress relief, and insomnia. Its higher concentration of cannabinoids can have a more immediate and strong effect. Our High CBD Chew contains two triple-doses of cannabinoids that provide a mild psychoactive effect. The ratio of THC to CBD creates an opiate-like affect that will allow you to function in daily life with less discomfort and none of the side effects or potential organ damage associated with pharmaceutical medications.